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KMID : 1204320100260020215
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Laboratory Animal Research
2010 Volume.26 No. 2 p.215 ~ p.218
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A Tumoral Calcinosis Case in a Beagle Dog
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Shin Sang-Kyung
Chang Dong-Woo
Na Ki-Jeong
Kim Gon-Hyung
Ahn Byeong-Woo
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Abstract
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We describe a case of tumoral calcinosis in a 13-month-old female Beagle dog presenting for surgical removal of a 4×3×3 ㎝ mass in the soft tissues of the medial right shoulder joint. On radiologic examination, the mass showed increased radiopacity. Blood analysis data indicated chronic renal failure with hyperphosphatemia and hypercalcemia. Grossly, the mass was irregular, round and multilocular, with hard consistency. Histologically, there were many variable-sized loculi surrounded by capsule and interstitial connective tissues were generated among the loculi. Inflammatory cells, fibroblasts, fibrocytes and multinucleated giant cells were present at the margins of the loculi. Most of the loculi were filled with calcium or chalky material. To our knowledge, this is the first case of tumoral calcinosis in Korea.
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KEYWORD
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Beagle dog, case report, tumoral calcinosis
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