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KMID : 1204320190350010013
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Laboratory Animal Research
2019 Volume.35 No. 1 p.13 ~ p.22
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The effects of coenzyme Q10 supplement on blood lipid indices and hepatic antioxidant defense system in SD rats fed a high cholesterol diet
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Kim Ha-Na
Jeon Dong-Gyung
Lim Yong
Jang In-Surk
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Abstract
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A total of 24 SD rats were allotted to four treatment groups such as the control (CON), 1% of cholesterol diet (CHO), 0.5% of coenzyme Q10 (COQ) and 1% of cholesterol plus 0.5% of coenzyme Q10 (CHCQ) groups to determine the effects of coenzyme Q10 (CoQ10) on the antioxidant defense system in rats. The body weight, weight gain, liver weight and abdominal fat pads were unaffected by 0.5% of CoQ10 supplement in the rats. The level of triglyceride and HDL-cholesterol levels in the blood was significantly increased (p
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KEYWORD
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Coenzyme Q10, Cholesterol, Antioxidant enzymes, Lipid indices
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