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KMID : 1225120100020010014
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Vascular Neurology
2010 Volume.2 No. 1 p.14 ~ p.17
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Current Strategies for the Treatment of Atherosclerotic Plaques
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Pae Hye-Kyong
Kim Gyung-Whan
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Abstract
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Lately, there has been an increasing awareness of the importance of total plaque area and morphology of the atherosclerotic plaque as a major risk factor for stroke and cerebrovascular disease. A number of investigators have proposed the use of B-mode ultrasonography to characterize plaque composition and to identify the higher-risk unstable carotid lesion. Recently, multiple studies have been investigated the role of intensive statin therapy for patients with atherosclerosis. In this review, we will provide a brief overview on methodology of B-mode ultrasonography and clinical trials of high-dose statin treatment. Furthermore, we will discuss the evidence for effects of high-dose statin treatment on atherosclerosis.
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KEYWORD
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Atherosclerosis, Carotid intima-media thickness, Atherosclerotic plaque, Echogenicity, B-mode ultrasonography, C-reactive protein, Low density lipoprotein-cholesterol
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