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KMID : 1225120110030010042
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Vascular Neurology
2011 Volume.3 No. 1 p.42 ~ p.44
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Imminent Fracture in a Patient with Atypical Femoral Fracture after Prolonged Use of Bisphosphonates
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Yoon Young-Kwon
Cho Sung-Rae
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Abstract
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Bisphosphonates have been the most widely prescribed drugs for the treatment of postmenopausal or senile osteoporosis, and they are highly effective in reducing the risk of vertebral and hip fractures in clinical trials. However, recent case series have implicated a link between prolonged therapy of bisphosphonates and atypical femoral fractures. A 68-year-old woman underwent sudden right hip pain without any trauma or falling history. Hip X-ray and pelvic computed tomography revealed subtrochanteric fracture of femur. She had been prescribed the bisphosphonates for approximately 5 years in order to treat osteoporosis. On the whole body bone scan, imminent fracture, subtrochanteric microcrack of left femur also showed an increase of focal uptake, which is symmetrical and opposite to the atypical fracture. The aim of this report is to present the experience of the imminent fracture in a patient who had a non-traumatic atypical femoral fracture such as subtrochanteric fracture after prolonged use of the bisphosphonates.
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KEYWORD
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Osteoporosis, Bisphosphonates, Femoral fracture
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