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KMID : 1225120180060010015
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Vascular Neurology
2018 Volume.6 No. 1 p.15 ~ p.18
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Autophagic Function in Atherothrombus Stabilization and Regression
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Cho Kyoung-Joo
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Abstract
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Atherosclerotic plaque formation is not irrevocable, and it as accepted that atherosclerosis could be regressed by statin treatment in clinic and experimental reports. In getting aging society, metabolic disorder become a major concern and also main cause leading cardio-and neuro-vascular disease such as atherosclerosis, stroke, and even cognitive decline. This is focusing on autophagic regression of atherosclerotic plaques. Some evidences indicate that autophagy occurs in atherosclerosis. Both in experimentally and clinically, this chapter shows that progressive plaque formation mechanism and regression under autophagic flow. On therapeutic, autophagy may be important to reveal the mechanism regressing atherosclerotic plaque.
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KEYWORD
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Autophagy, Atherosclerosis, Atherothrombus
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