KMID : 1234420100380040414
|
|
Korean Journal of Microbiololgy and Biotechnology 2010 Volume.38 No. 4 p.414 ~ p.419
|
|
Anti-Oxidant Property and Inhibition of Melanin Synthesis of Eight Plant Extracts
|
|
Kim Jae-Young
Lee Jin-Young Lee Wi-Young Yi Yong-Sub Lim Yoong-Ho
|
|
Abstract
|
|
|
Fig (Ficus carica L.) belongs to the mulberry tree (Moraceae) which is one of the oldest fruits in the world. It has been used as a digestion promoter and a cure for ulcerative inflammation and eruption in Korea. The present study investigated the antimicrobial activity of methanol (MeOH) extract of fig leaves against methicillin- resistant Staphylococcus aureus (MRSA) isolated in clinic. The MeOH extract (MICs, 2.5 to 20 mg/mL; MBCs, 5 to 20 mg/mL) was demonstrated as antibacterial activity in isolates MRSA 1-20. The administration of the MeOH extract in combination with oxacillin or ampicillin induced a reduction of ¡Ã4-8-fold in all tested bacteria, which was considered to be synergistic based on a FICI of ¡Â 0.375-0.5. Furthermore, time-kill study was found that a combination of MeOH extract with oxacillin or ampicillin produced a more rapid decrease in the concentration of bacteria CFU/mL than MeOH extract alone. The results suggest that fig leaves could be employed as a natural antibacterial agent in MRSA infection care products.
|
|
KEYWORD
|
|
Antioxidant activity, tyrosinase inhibition, plant extracts, depigmentation agent
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|