|
KMID : 1236020180460040372
|
|
Microbiology and Biotechnology Letters
2018 Volume.46 No. 4 p.372 ~ p.376
|
|
|
In-vitro Anti-thrombosis Activities of Different Parts of Nelumbo nucifera Gaertner
|
|
An Seon-Mi
Sung Hwa-Jung
Kim Jong-Sik
Park Jong-Yi
Sohn Ho-Yong
|
|
|
Abstract
|
|
|
|
To investigate the bio-activities of lotus (Nelumbo nucifera Gaertner), ethanol extracts were prepared from different parts of lotus, including lotus root, node of root (NR), leaf, pod of seed (PS), seed (S), and embryo of seed (ES), respectively. Anti-thrombosis activities were evaluated. NR, S, and PS extracts displayed strong anti-coagulation activities, as evidenced by the inhibition of thrombin, prothrombin, and coagulation factors, respectively. NR, leaf, S, and PS extracts displayed strong platelet aggregation inhibitory activities. The aggregation inhibition of S and PS extract was comparable to that of aspirin. The extracts of NR, S, and PS did not show hemolysis activity up to 1.0 mg/ml.
|
|
|
KEYWORD
|
|
|
Anti-coagulation, anti-platelet aggregation, lotus, Nelumbo nucifera Gaertner
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|