KMID : 1239920070010030189
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Nutrition Research and Practice 2007 Volume.1 No. 3 p.189 ~ p.194
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The antioxidant and cytotoxic activities of Sonchus oleraceus L. extracts
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Yin Jie
Wang Myeong-Hyeon Kwon Gu-Joong
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Abstract
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This study investigated in vitro antioxidant activity of Sonchus oleraceus L. by extraction solvent, which were examined by reducing power, hydroxyl radical-scavenging activity(HRSA) and 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assays. 70% MeOH extract had the greatest reducing power while EtOH extract had the greatest HRSA. The antioxidant activity of S. oleraceus extracts was concentration dependent and its IC50 values ranged from 47.1 to 210.5 ¥ìg/ml and IC50 of 70% MeOH, boiling water and 70% EtOH extracts were 47.1, 52.7 and 56.5 ¥ìg/ml, respectively. 70% MeOH extract of S. oleraceus contained the greatest amount of both phenolic and flavonoid contents. The extracts tested had greater nitrite scavenging effects at lower pH conditions. The cytotoxic activity showed that EtOH extract had the best activity against
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KEYWORD
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Sonchus oleraceus L, Antioxidant, Cytotoxic, Phenolic content, Nitrite scavenging activity
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