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KMID : 1812320220390020168
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Journal of Yeungnam Medical Science
2022 Volume.39 No. 2 p.168 ~ p.171
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Palisaded encapsulated neuroma on the lower lip: a case report
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Seol Jung-Eun
Hong Seong-Min
Ahn Sang-Woo
Kim Jong-Uk
Jin Woo-Jung
Park So-Hee
Kim Hyo-Jin
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Abstract
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Palisading encapsulated neuroma is a rare, benign, cutaneous nerve sheath tumor. It usually occurs as an asymptomatic solitary skin-colored papule and commonly affects the nose and cheeks. Sometimes, it involves other sites, including the shoulder, upper arm, and trunk, but rarely involves the oral mucosa, including that of the lip. In our case, a 63-year-old female patient complained of a pinkish rubbery nodule on her lower lip. Histopathologic examination demonstrated a well-circumscribed nodule encapsulated by connective tissue stroma in the dermis. The nodule consisted of palisading spindle-shaped tumor cells with wavy and basophilic nuclei. The cells were arranged in streaming fascicles with multiple clefts and were strongly positive for S-100 proteins. To our knowledge, only three cases of palisading encapsulated neuroma on the lower lip have been reported in the Korean literature. Herein, we report a rare case of an oral palisaded encapsulated neuroma.
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KEYWORD
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Lip, Nerve sheath neoplasms, Neuroma
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