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KMID : 1812320230400030241
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Journal of Yeungnam Medical Science
2023 Volume.40 No. 3 p.241 ~ p.246
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Advances in management of pediatric chronic immune thrombocytopenia: a narrative review
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Lee Jae-Min
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Abstract
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Immune thrombocytopenia (ITP) is a disease in which thrombocytopenia occurs because of immune-mediated platelet destruction and decreased platelet production. Although many pediatric patients with ITP experience spontaneous remission or reach remission within 12 months of first-line therapy, approximately 20% progress to chronic ITP. Patients who do not respond to first-line treatment or experience frequent relapses are of great concern to physicians. This review summarizes recent treatments for second-line treatment of pediatric chronic ITP.
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KEYWORD
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Dapsone, Idiopathic thrombocytopenic purpura, Rituximab, Splenectomy, Thrombopoietin
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