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KMID : 1813520150040020046
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Journal of the Korean Glaucoma Society
2015 Volume.4 No. 2 p.46 ~ p.54
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Measurement of Retinal Nerve Fiber Layer Thickness by Optical Coherence Tomography and Scanning Laser Polarimetry in Myopic Eyes with Peripapillary Atrophy
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Hwang Young-Hoon
Lee Bong-Eun
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Abstract
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Purpose : To determine how myopia and peripapillary atrophy (PPA) affect the measurement of retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT) and scanning laser polarimetry (GDx) with variable and enhanced corneal compensation (VCC and ECC).
Methods : We measured RNFL thickness in 20 eyes from 20 subjects without glaucoma and with myopic PPA (PPA group) and 20 eyes from 20 normal subjects without PPA (control group) with various scan circle sizes by OCT, GDx-VCC and GDx-ECC.
Results : On OCT analysis, the individual clock-hour RNFL thickness of the PPA group was significantly less than that of the control group in the nasal, superior and inferior areas, whereas the thickness was similar in the temporal area where PPA was most commonly seen. On GDx-VCC and GDx-ECC analyses, the individual clock-hour RNFL thickness of the PPA group was similar or less in the nasal, superior and inferior areas than that of the control group, whereas the thickness was greater in the PPA group than in the control group in the temporal area. This RNFL thickness pattern seen with both OCT and GDx measurement was consistent for all the scan circle sizes even though the scan circle was large enough that it did not encompass the PPA area.
Conclusions : When measured by OCT and GDx, the thickening of the RNFL in the temporal area was observed in the PPA group. Our results suggest that PPA per se may not be responsible for the temporal thickening of RNFL in myopic eyes with PPA.
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KEYWORD
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Glaucoma, Myopia, Optical coherence tomography, Retinal nerve fiber layer
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