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KMID : 1813520160050020027
Journal of the Korean Glaucoma Society
2016 Volume.5 No. 2 p.27 ~ p.31
Effect of Topical Anesthesia on Intraocular Pressure Measured by iCare Rebound Tonometer
Jung Yun

Lee Jong-Yeon
Yoo Chung-Kwon
Kim Yong-Yeon
Abstract
Purpose : To investigate whether topical anesthesia affects intraocular pressure (IOP) reading obtained with iCare rebound tonometer (RT).

Methods : A total of eighty eyes of 40 healthy subjects were included. Both eyes were divided into two groups (0.5% proparacaine hydrochloride or 0.5% carboxymethylcellulose sodium). Central cornea thickness (CCT) was obtained with specular microscopy and IOP was measured with RT at baseline. CCT and IOP were measured at 1 minute after instillation of either of the two eye drops.

Results : IOPs measured by RT decreased significantly after instillation of a single drop of 0.5% proparacaine hydrochloride (13.00 to 12.00 mmHg, median value, p < 0.001) or, 0.5% carboxymethylcellulose sodium (13.00 to 12.75 mmHg, median value, p = 0.02) compared to the pre-instillation IOP readings. The magnitude of IOP reduction seen after instillation of 0.5% proparacaine hydrochloride was significantly greater than CMC group. (1 mmHg vs. 0.25 mmHg, median value, p < 0.001). No significant changes in CCT change was observed in both groups.

Conclusions : When instilled prior to rebound tonometry, both 0.5% proparacaine hydrochloride and 0.5% carboxymethylcellulose sodium eye drops decreased IOPs. The 0.5% proparacaine hydrochloride may have a greater IOP-lowering effect than 0.5% carboxymethylcellulose sodium eye drop.
KEYWORD
Intraocular pressure, Anesthesia
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