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KMID : 1813520170060010016
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Journal of the Korean Glaucoma Society
2017 Volume.6 No. 1 p.16 ~ p.24
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Predictive Factors Associated with Short-term and Long-term Outcomes of Half Angle Selective Laser Trabeculoplasty
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Han Jong-Chul
Suh Wool
Kim Si-Bum
Park Seun-Ja
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Abstract
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Purpose : To evaluate the diagnostic capability of quantified optic nerve head (ONH) depth analysis system incorporated in the Nonmyd-WX 3D retina camera (Kowa, Tokyo, Japan) in discriminating between glaucoma suspects and glaucoma subjects.
Methods : The present study included the eyes with unilateral or bilateral primary open angle glaucoma (POAG) using maximal dose glaucoma medications. Success was defined as an intraocular pressure (IOP) reduction ≥ 20% compared to baseline. To investigate the factors associated with short-term and long-term response to SLT, univariate and multivariate logistic regression analyses using a generalized estimating equation model were performed.
Results : In this study, 184 eyes in 147 patients were included. In multivariate analysis, higher baseline IOP was associated with positive short-term and long-term response (p = 0.026; p = 0.019, respectively). Secondary treatment was associated with negative short-term and long-term response in multivariate analysis (p = 0.006; p = 0.008, respectively). Severe trabecular meshwork (TM) pigmentation was associated with positive short-term response (p = 0.019). The correlation between IOP responses in both eyes was significant at 1 month and 6 months postoperatively (p < 0.001; p = 0.006, respectively). The correlation between IOP responses on primary and secondary half angle SLT treatments was significant at 3 months and 6 months postoperatively (p = 0.003; p = 0.005, respectively).
Conclusions : Short-term and long-term outcomes of half angle SLT were positively associated with baseline IOP and negatively associated with secondary SLT treatment. Severe TM pigmentation was positively associated with short-term response of SLT. IOP response correlations between bilateral treatment cases and between primary and secondary SLT were significant.
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KEYWORD
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Trabecular meshwork, Glaucoma, Lasers
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