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KMID : 1813520190080010021
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Journal of the Korean Glaucoma Society
2019 Volume.8 No. 1 p.21 ~ p.27
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Relationship between Retinal Nerve Fiber Layer Thickness and Early Glaucomatous Changes in the Adolescents
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Lee Na-Young
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Abstract
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Purpose : To evaluate of usefulness of retinal nerve fiber layer thickness as measured by optical coherence tomography (OCT) in children and young adolescents in the diagnosis of glaucoma, ocular hypertension, and glaucoma suspect.
Methods : In total, 234 patients aged <18 years were included in this study (21 eyes with glaucoma, 179 suspected glaucoma eyes, and 34 eyes with ocular hypertension). All patients underwent OCT to measure the retinal nerve fiber layer thickness, Humphrey visual field testing if possible, and other ocular examinations. Based on the OCT results, we classified the eyes into 4 o'clock-hour and 12 o'clock-hour sectors and compared these data with other clinical ocular findings.
Results : The retinal nerve fiber layer thickness as measured by OCT was correlated with the vertical cup disc ratio. An OCT 330° (Sup) value of <140 μm or an average OCT value of <105 μm is useful for the prediction of a vertical cup disc ratio of >0.6.
Conclusions : A higher vertical cup disc ratio is associated with a lower retinal nerve fiber layer thickness, not only with back-bowing of the lamina cribrosa or normal variation. An OCT 330° (Sup) value of <140 μm or average OCT value of <105 μm is a useful index with which to predict early glaucomatous changes in pediatric and young adolescent patients.
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KEYWORD
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Childhood glaucoma, Glaucoma suspect, Nerve fiber layer thickness, Ocular hypertension, Optical coherence tomography
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