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KMID : 1813520210100020055
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Journal of the Korean Glaucoma Society
2021 Volume.10 No. 2 p.55 ~ p.62
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Comparison of Visual Field Progression Detection between Event- and Trend-based Analyses in Patients with Open-angle Glaucoma
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Lee Ji-Hei
Park Chang-Keum
Park Sung-Eunk
Bae Hyoung-Won
Choi Wung-Rak
Lee Sang-Yeop
Seong Gong-Je
Kim Chan-Yun
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Abstract
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Purpose : The aim of this study was to compare the performances of event- and trend-based analyses of visual field (VF) tests in different glaucoma severities and VF defect locations.
Methods : A retrospective review was conducted to include 258 eyes of 159 patients diagnosed with open-angle glaucoma. A minimum of five reliable VF tests were required for analysis. VF progression was detected with guided progression analysis (GPA II) software of Humphrey field analyzer and patients were categorized into following groups depending on the results: T+E+ (progression detected by both trend and event-based analyses), T+E- (progression detected only by trend-based analysis), T-E+ (progression detected only by event-based analysis), and T-E-groups (progression not detected in either analysis).
Results : Patients were followed for 5.1 ± 2.0 years. Out of 258 eyes, 43 eyes showed progression by either event or trend-based analysis. The agreement between the two analyses was found to be fair. No difference was found in detection rate, mean detection time or the number of VF tests taken. The trend-based analysis tended to detect progression more frequently in eyes with more severe baseline VF. The event-based analysis fared worse in detection of central VF progression within 20°.
Conclusions : Trend- and event-based analyses performed similarly in detection of functional progression in glaucoma. Trend-based analysis detected progression more commonly in glaucoma with advanced VF defects, and event-based analysis more commonly detected VF defects in the periphery. Clinicians should assess both analyses when determining progression of VF damage in a clinical setting.
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KEYWORD
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Disease progression, Glaucoma, Visual field
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