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KMID : 4412620170230010024
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Clinical Hypertension
2017 Volume.23 No. 1 p.24 ~ p.24
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Blunted heart rate recovery is associated with coronary artery spasm in patients with suspected vasospastic angina
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Kim Hyun-Su
Cho Sang-Hoon
Cho Kyoung-Im
Kim Bong-Joon
Im Sung-Il
Heo Jung-Ho
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Abstract
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Background: Autonomic nervous system activity has been shown to be altered in patients with vasospastic angina (VA). Heart rate recovery (HRR) is a simple, non-invasive measurement of autonomic nervous system dysfunction. We aimed to investigate whether HRR is related to VA, as established by an ergonovine test.
Methods: A total of 976 consecutive patients (47.5% male, mean age 55 years) without significant coronary artery disease who underwent both an ergonovine provocation test and a treadmill exercise test were enrolled. The relationship between VA and HRR was evaluated.
Results: A total of 30.7% (300/976) of patients were diagnosed with VA, as documented by the ergonovine provocation test. HRR was significantly reduced in patients with VA compared to patients without VA (24.6?±?18.0 vs. 30.5?±?22.2, p?
Conclusion: Blunted HRR was an independent predictor of VA presence, which suggests a link between coronary artery spasm and autonomic dysregulation.
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KEYWORD
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Coronary artery spasm, Cardiac autonomic function, Heart rate recovery
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