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KMID : 4412620180240010014
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Clinical Hypertension
2018 Volume.24 No. 1 p.14 ~ p.14
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Metabolic syndrome, not menopause, is a risk factor for hypertension in peri-menopausal women
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Oh Gyu-Chul
Kang Kee-Soo
Park Chan-Soon
Sung Ho-Kyung
Ha Kyoung-Hwa
Kim Hyeon-Chang
Park Sung-Ha
Ihm Sang-Hyun
Lee Hae-Young
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Abstract
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Background: It has been long debated whether menopause itself is a risk factor for hypertension in peri-menopausal women. We aimed to assess the association between menopause and hypertension, and whether metabolic syndrome (MetS) has an influence on its effect.
Methods: Data for 1502 women aged 42 to 53 from the Korean Genome and Epidemiology Study (KoGES) database were retrospectively analyzed. The KoGES database consists of 10,038 participants, of which 52.6% (5275) were female. Subjects were followed up for 4 years, and compared according to menopausal status. Additionally, 1216 non-hypertensive subjects were separately analyzed to assess whether a change in menopausal status was associated with development of hypertension.
Results: The prevalence of hypertension, diabetes, and MetS for menopausal and non-menopausal subjects at baseline was 24.4% vs. 16.7%, 5.8% vs. 2.9%, and 25.4% vs. 16.6%, respectively (p?
Conclusions: Menopause is closely associated with increased incidence of hypertension, but the increase may not be attributable to menopause itself but to increased prevalence of MetS.
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KEYWORD
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Hypertension, Metabolic syndrome, Menopause, Obesity
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