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KMID : 0352319810040000153
Journal of KyungHee Oriental Medicine College
1981 Volume.4 No. 0 p.153 ~ p.159
An Effect of Jeogunbackpiwhan Administration on the Mucous Cell in Doudenum of the Rat


Abstract
In order to study the effect of Jeogundackpiwhan on the mucous cell in the duodenum of rat, the experimental animals were administrated with 2mg per gm body weight of Jeogunbackpiwan through oral cavity. They were sacrified by ether anesthesia and obtained from duodenum and fixed in 10% neutral formalin. After embedded in paraffin, sectioned in 6-7 micrometer thickness, and stained with P.A.S. periodic acid Schiff s reaction. The average number of the mucous cell was counted in each specimen over 50 fields under 450 magnification.
The following results were obtained.
1. Total numbers of mucous cell in normal group was 26.7 9.3 but it was increased by time lapased high value 12hrs group 33.8 9.3 after it was according to de-creased 48hrsigroup 24.7 6.1 by time lapased.
2. A type mucotise cell comparable gradually increased experimental group 48hrs high value.
3. B type mucouse cells were decreased comparable between normal group and experimental group 6hrs and 12hrs group the lowest value after it was time lapased gradually in creasing 48hrs group high value.
4. C type increased by time lapased 12hrs high value and gradually decreased recovery 48 his showed tendency normal group.
5. According to the above findings it is presumed that Jeogundackpiwhan accelerate discharge.
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