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KMID : 0352319810040000271
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Journal of KyungHee Oriental Medicine College
1981 Volume.4 No. 0 p.271 ~ p.276
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Effects on the secretion of Gastrin and Uropepsin of rats treated with Coptidis Rhizoma, Scutellariae Radix and Phellodendri Cortex
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Abstract
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Each decoction of Coptidis Rhizoma, Scutellariae Radix and Phellodendri Cortex was orally administrated to the rats. And the effects on the Gastrin and Uropepsin secretions were observed.
The results were as follows:
1. The effects on the secretion of Gastrin in the experimental groups administered each with Coptidis Rhizoma and Scutellariae Radix comparing with the normal group, showed significant values P < 0.05, P < 0.02, P < 0.01 and P < 0.001 separately. However the group medicated with Phellodendri Cortex showed significant values only 30 minutes after the administration.
2. Uropepsin level in the experimental group administered each with Coptidis Rhizoma and Phellodendri Cortex, comparing with the normal group, showed highly significant statistic values (P < 0.001): Another experimental group medicated with Scutellariae Radix showed significantly statistical values (P < 0.001) 240 minutes after the administration.
3. According to the above mentioned results it was conculuded that the secretion of Gastrin in plasma and Uropepsin content of urine in albino rats treated with Coptidis Rhizoma decoction were remarkably increased as comparing with Scutellariae Radix and Phellodendri Cortex decoction.
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