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KMID : 0352319810040000285
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Journal of KyungHee Oriental Medicine College
1981 Volume.4 No. 0 p.285 ~ p.294
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Experimental Studies on the Anti-Inflammatory, Analgesic Effects of Pilyongbangkamgil-Tang and Kamipilyongbangkamgil-Tang on Rats and Mice
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Park Hang-Ki
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Abstract
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According to oriental clinic effect findings hitherto, pilyongbangKamgil-Tang has been curative effects on chronic pharyngitis, acute tensillitis and angina.
Auther tried to make clear the anti-inflammatory effect on rat paw which has become edema formation by 5% of acetic acid/saline solution. and the analgesic effect on mouse thorough method of acetic acid because the medicine decoction of KamipilyongbangKamgil-Tang, PilyongbangKamgil-Tang, and the extracted powder of pilyongbangKamgil-Tang are prescribed to rat and mouse.
In present report, anti-inflammatory, analgesic effects of pilyongnangKamKil-Tang, the extracted powder of the above prescription, and KamipilyongbangKamgil-Tang were proved by the following test.
The results are summarized as follows.
1. KamipilyongbangKamgil-Tang (liquid), pilyongbangKamgil-Tang and the extracted powder of pilyongbangKamgil-Tang were tested for analgesic effects; KamipilyongbangKamgil-Tang has the most effective analgesic function, then pilyongbangKamgil-Tang, then the extracted powder, and I found that the t-test of those above prescriptions, in this order, should come to the result of voluntariness P < 0.001, P < 0.02, and P < 0.05 respectively.
2. Analgesic effects of pilyongbangKamgil-Tang and the extracted powder against the mouse pain induced acetic acid have been strengthened by increase of double dosage and 4 fold dosage.
3. With pilyongbangKamgil-Tang and KamipilyongbangKamgil-Tang prescribed for rat, the increasing and the inhibitory rate of rat paw edema formation showed
significantly statistical values, and the anti-inflammatory effect of the extracted powder of pilyongbangKamgil-Tang is not supported so long than pilyongbang-KamgilTang.
4. The anti-inflammatory effect of KamipilyongbangKamgilTang on the edema formed at the rat paw showed si ificantly statistical value than the other sample.
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