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KMID : 0352319830060000153
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Journal of KyungHee Oriental Medicine College
1983 Volume.6 No. 0 p.153 ~ p.167
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A Study on the Decursin content of Dang-Gwi and it´s Effect on the Hematopoiesis in Anemic Rabbit
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Abstract
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A series of experiment was conducted for the purpose to determine decursin content of various Dang-Gwi (´ ) species frequently prescr: bed for the blood supplementation and menstrual regulation in oriental medicine together with their .iematopoietic effectiveness in rabbit induced to be anemic by phenylhydrazine hydrochloride treatment or in hypoprothrombinemic mouse due to warfarin treatment in the latter case the blood clotting effect was determined by various part of Dang-Gwi () root.
1. No decursin was detected in both Angelica sinensis and Angelica acutiloba but it was found in the
case of Angelica gigas. The amount of decursin content was found to be 5.93% fo wild Angelica gigas,
5.94% for cultivated Angelica gigas in CHUN YANG, 6.31% for cultivated Angelica gigas in KI RIN
and 6.63% for cultivated Angelica gigas in DAE HWA.
2. Hematopoietic effect was found for wild Angelica gigas, cultivated Angelica gigas, Angelica sinensis and Angelica acutiloba regardless the origin in statistical term.
3. No difference in the plasma prothrombin time in normal mouse or the blood clotting effectiveness in hypoprothrombinemic mouse due to warfarin treatment under the influence of various parts of Angelicae gigantis Radix was found.
In view of the above findings, hematopoietic effect was identified for Dang-Gwi ( 1fi ) but it is concluded that no blood clotting effect is found according to the various part of it´s root and its medical application is meaningless.
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