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KMID : 0352319840070000273
Journal of KyungHee Oriental Medicine College
1984 Volume.7 No. 0 p.273 ~ p.285
Experimental Studies on the Effects of Yangkyuksanhwatang


Abstract
In order to investigate experimentally the clinical effects of Yangkyuksanhwatang that was prescribed to cure the Hyungkyukyuljng of Soyang - In, the author experimented various activities of mixed extract from the Yangkyuksanhwatang (S - I) and a mixture of individual extracts from each herb in Yangkyuksanhwatang (S - II) by the method prescribed in the experimental part.
The results of the studies were summarized as follows;
1) In acetic acid method experiment, analgesic effects were noted and the same effects were obtained in a pressure pain threshold study on the rat hind paws.
2) Suppressive actions were not shown on the convulsion induced by Shy "nine but significant effects were noted on the convulsion induced by picrotoxin.
3) A prolongation of anesthetic time by Pentobarbital sodium and antipyretic effect were observed.
4) Relaxing actions were noted on the ileums of mice, also same effects were recognized on contraction of the ileums due to Acetylcholine and Barium chloride.
5) The expansion of blood vessel by relaxation of smooth muscle and the fall of blood pressure were noted.
6) Generally S - I revealed superior effect in comparison with S - II.
According to the above results, effects based on the oriental medical references were approximate to the actual experimental results.
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