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KMID : 0352319840070000323
Journal of KyungHee Oriental Medicine College
1984 Volume.7 No. 0 p.323 ~ p.334
A Study of Effects of Insampaedok-san and Kamiinsampaedok-San on the Analgesia, Antipyresis and Thioacetamide induced liver damage in rats and mice


Abstract
An experimental study was done to reserch the clinical effects of Insampaedok - San on the analgesia, antipyretic and liver damage in rats and mice.
The results obtained as follows.
1) All cases of sample group showed significance in the analgesic action. In these group, dried extracted powder of Kamiinsampaedok - San showed the highest significance.
2) Antipyretic effect is noted to be significant in dried extracted powder of Insampaedok - San, dried extracted powder of Kamiinsampaedok - San and each dried extracted powder of Kamiinsampaedok - San, but each dried extracted powder of Insampaedok - San is not significant.
3) All cases of Sample group in S - GOT activity revealed the significant decrease rate in proportion to control group, especially dried extracted powder of Insampaedok - San showed the higest significance.
4) All cases of sample group on S - GPT activity revealed the significant decrease rate in proportion to control group, especially dried extracted powder of Insampaedok - San and dried extracted powder of Kamiinsampaedok - San showed the highest significance.
5) In the lactic dehydrogenase activity in Serum, all cases of sample group showed significant decrease rate in proportion to control group. Especially dried extracted powdei of Insampaedok - San.
According to the above findings, there are analgesic and antipyretic effects in both
of the dried extracted powder of Insampaedok - San and Kamiinsampaedok - San
expecially prominant in Kamiinsampaedok - San. The dried extracted powder of
Insampaedok - San and Kamiinsampaedok - San revealed a significant effect to the
activity of GOT, GPT, and LDH of damaged liver. It is thought that the reason
each dried extracted powder compound of Kamiinsampaedok - San revealed less
significant action since there were no counteraction abtaining by boiling mixture all
of the herb medicine.
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