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KMID : 0352319850080000309
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Journal of KyungHee Oriental Medicine College
1985 Volume.8 No. 0 p.309 ~ p.321
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Effect of Backchulsan on Goblet Cell in Duodenum of the Rat
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Abstract
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In order to study the effect of Backchulsan on the goblet cell in duodenum of the rat, the experimental animals were administrated with 1 mQ per 200 g body weight of Backchulsan after castor oil through oral cavity. They were sacrified and obtained from duodenum, and fixed in 10% neutral formalin. After embedded in paraffin, sectioned in 5 micrometer thickness, and stained with P.A.S. (periodic acid Schiff´s) reaction. The average number of the goblet cells were counted in each specimen over 60 fields under 400 magnification.
The following results were obtained:
1) Type A in the goblet cells were increased at the 3 hours after treated with Backchulsan in comparision with that of control group administrated of castor oil.
2) Type B in the goblet cells were increased at the 3 hours after treated with Backchulsan in comparision with that of control group administrated of costor oil.
3) Type C in the goblet cells were decreased at the 6 hours after treated with Backchulsan in comparision with that of control group administrated of castor oil.
4) The average number of the goblet cells were decreased at the 6 hours after treated with Backchulsan in comparision with that of control group administrated of castor oil.
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