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KMID : 0354619920040010321
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Journal Dankook Dental Research Institute
1992 Volume.4 No. 1 p.321 ~ p.330
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Evaluation of Mandibular Condyle Position in TMJ Transcranial Radiograph
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Abstract
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Formocresol(FC) had been widely used as medicament for pulpotomy, but because FC have strong toxicity, carcinogenic potential, and strong diffusible properties in tissues, Glutaraldehyde, another medicament for pulpotomy was greatly presented by
many
investigators and practitioners. Although many investigators had studied difference of two medicament's effects on periodontal tissues and tooth germ, there were no manuscripts of cellular activity about these medicaments applied to teeth, but
theeth,
but there were almost clinical, histopathological studies, Especially in the investigative effects on tooth germ, the results were controversal. Thus to investigate about effects on cellular actiity of perigerminal tissue and tooth germ of rat,
author
presented the cellular activity and the pathologic change through calculating Thymidine labelling index(TLI) from autoradiographic technique using 3H-thymidine after these medicaments were applied to tooth.
@ES The obtained results were as follows.
@EN 1. Inflammation was initiated after one week of FC and two weeks of GA. It was thought that diffusible property of GA was lesser than that FC.
2. In group treated with FC, inflammation vasodilation and bone destruction continuously increased for all periods of experiment and the feature of 8 weeks was very severe. But in group treated with GA, inflammation, vasodilation and bone
destruction
slightly increased for all period of experment.
3. TLI was increased after two weeks of FC, but decreased after four weeks because of different accumulative concentration between 2 and 4 weeks.
4. GA treated group which did not show the change of the cellular activity of perigerminal tissue and tooth germ presented the slight effects on these cells.
5. Changes of cellular activities in FC treated group did not result from inflammation, but formocresole's property iteif. And bone destruction was derived from secondary effects of inflammation.
6. The fact that FC arose severe inflammation and change of cellular activity reflected that FC might affected.
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KEYWORD
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