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KMID : 0359020070350020068
Korean Journal of Gastrointestinal Endoscopy
2007 Volume.35 No. 2 p.68 ~ p.73
The Significance of Fecal Occult Blood Testing to Screen for Colon Cancer
Kwon Jung-Hyun

Choi Myung-Gyu
Suh Jung-Pil
Chang Jae-Hyuck
Nam Kwan-Woo
Park Ho-Sung
Paik Chang-Nyol
Park Jae-Myung
Cho Yu-Kyung
Lee In-Seok
Kim Sang-Woo
Chung In-Sik
Abstract
Background/Aims:We investigated the efficacy of the fecal occult blood test (FOBT) as a colon cancer screening tool in a tertiary hospital setting.

Methods:This retrospective study analyzed patients who underwent routine check- ups at Kang-Nam St. Mary¡¯s Hospital Health Promotion Center from January 2004 to April 2005. All the subjects were encouraged to submit stool for a FOBT, while performing a double contrast barium enema (DCBE) was optional for those who wanted colon examination. Colonoscopy was performed if the FOBT or DCBE results were abnormal or if the patients had bowel symptoms.

Results:The FOBT was performed in 8,198 of 10,182 patients (80.5%) who underwent routine check-ups. The overall positive rate of FOBT was 149 of 8,198 (1.8%) and this increased with age (p£¼0.05). Colonoscopy and/or DCBE was performed in 33 of 149 patients (22.1%) in the FOBT positive group. Colon cancer and polyp were diagnosed 2 (6.1%) and 7 (21.2%) patients, respectively, in the FOBT positive group, whereas colon cancer and polyp were diagnosed in 3 (0.5%) and 102 (15.7%) patients, respectively, in the FOBT negative group. The sensitivity and specificity of the FOBT for colon cancer was 40% and 95.4%, respectively.

Conclusions:Although it had low sensitivity, the FOBT was a useful screening tool for detecting colon cancer in a tertiary hospital setting.
KEYWORD
Fecal occult blood test (FOBT), Colon cancer screening
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