KMID : 0359020100400020102
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Korean Journal of Gastrointestinal Endoscopy 2010 Volume.40 No. 2 p.102 ~ p.106
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A Case of Gastric, Duodenal and Colonic Metastases from Adenocarcinoma of the Lung
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Hwang Sang-Youn
Ahn Dong-Won Yon Woong-Jae Jeong Ji-Bong Kim Won Jung Yong-Jin Kim Byeong-Gwan Lee Kook-Lae
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Abstract
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Gastrointestinal metastasis of primary lung carcinoma is very rare, although this is found in about 4.7¡14% of cases at autopsy. An 81-year-old man was admitted with masses in the lung, adrenal gland, bladder and colon on his CT scans. We suspected metastases of an unknown origin and we carried out EGD and colonoscopy to differentiate the primary origin of the metastases. The examination revealed a submucosal tumor-like mass with central erosion on the gastric antrum and colonic splenic flexure, and polypoid lesions with a central fissure on the second portion of the duodenum. All the endoscopic forcep biopsies showed poorly differentiated adenocarcinoma without evidence of foci of the preinvasive surface glandular lesions. Immunochemical analysis of the tumor cells showed positivity for thyroid transcription factor-1 and cytokeratin 7, and negativity for cytokeratin 20 and caudal-related homeobox 2. Therefore, we diagnosed this case as multiple gastrointestinal metastases of primary lung cancer. This is first case of gastric, duodenal and colonic metastases from adenocarcinoma of the lung in the medical literature.
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KEYWORD
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Gastrointestinal metastases, Primary lung cancer
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