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KMID : 0359020100410060390
Korean Journal of Gastrointestinal Endoscopy
2010 Volume.41 No. 6 p.390 ~ p.393
The Solitary Polypoid Ganglioneuroma of the Ascending Colon
Jung Yong-Wook

Jang Byung-Ik
Jang Kyoung-Ae
Kim Kyeong-Ok
Kim Mi-Jin
Abstract
Ganglioneuromas are neuroectodermal tumors composed of varying amount of ganglion cells, nerve fibers, supporting cells of the enteric nervous system. Ganglioneuromas of the GI tract are rare tumors. A 50-year-old man came to our hospital due to the mass of liver and adrenal gland which was examined with ultrasonography at local medical center. On admission, abdominal magnetic resonance imaging was taken and liver biopsy was done. The mass of liver was hyperplastic nodule. At colonoscopy, about 0.3∼0.8 cm sized six polyps were noted. Except the 0.6 cm sized semipedunculated polyp of the ascending colon, the others were tubular adenomas. Histological examination of the polyp of the ascending colon revealed localized proliferation of nerve fibers and ganglion cells. These cells are positive for S-100 protein by immunihistochemistry. Therefore, he was diagnosed with polypoid ganglioneuroma of the ascending colon. We report this case because the solitary ganglioneuroma in large intestine without systemic disease was rare.
KEYWORD
Ganglioneuroma, Large intestine, S-100 protein
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학술진흥재단(KCI) KoreaMed 대한의학회 회원