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KMID : 0359319730130020119
Korean Journal of Veterinary Research
1973 Volume.13 No. 2 p.119 ~ p.129
Effect of Experimental Electrization Stress on the Pathogenesis of Escherichia coli in Mice

Abstract
A hypothesis that is a stress condition in animal may cause either enhancement or reduction of the host resistance against microbial infection was experimentally studied. Among of many processes for stress formation an experimental electrization in mice was devised, on the bases of blood picture analysis, and studied the effect of experimental electrization of mice on E. coll infection. The results obtained were as follows.
1. Electrization with ordinary current, A. C. 60 cps., on the path of symmetrical line of both posterior limbs at 20 to 100 volts (less than 10 ㎃) for 15 to 30 seconds was able to induce a stress reaction in blood pattern without showing any dangers of electrocution, electric burns and other residual signs, and no correlation between blood pattern of the reaction and an amount of current between 20 to 100 volts was observed. As the electrodes, two of 21 gauge hypodermic needles were used, when the electrization each of them were inserted into the center of toe tissue of the both legs.
2. Serum protein fractions following the experimental electrization showed a tendency of a low A/G ratio and a high value of α-globulin.
3. In the studies on the effect of electrical stress on the pathogenesis of E. coli in mice, a group in which a simultaneous electrization and infection, and a group infected two hours after electrization showed 80 per cent mortality. On the other hand, infection after 20 hours electrization and control groups showed their mortality of 40 and 60 per cent respectively.
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학술진흥재단(KCI)