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KMID : 0359319750150020223
Korean Journal of Veterinary Research
1975 Volume.15 No. 2 p.223 ~ p.231
Light and Electron Microscopic Studies on Distribution , Secretion and Formation of Pepsinogen Granules in Chickens

Abstract
In mammals there are two distinct cellular units of the gastric glands which are responsible for the secretion of acid and pepsin respectively, namely, the parietal cells for acid and the peptic or chief cells for pepsin. On the other hand, the bird does net have separate parietal and chief cells in the glandular stomach. There exist only a single cell type in the asian gastric secretory-glands.
In spite of this single cell type, however, variation in pepsin and acid secretion can he seen. Present study was conducted to know distribution, secretion and formation of the pepsinogen granules in chicken and rat stomach which observing by light and electron microscope.
1. In chicken, the pepsinogen granules are distributed in all submucosal gland cells and yet there are no distinction of parietal and chief cells. In rat, the pepsinogen granules are distributed in chief cells which lined the lower two-thirds of the gastric tubles and the parietal cells occupy upper third of the tub1e.
2. Carbachol markedly stimulates the secretion of pepsinogen granules in chiton and rat, but Histamine is slightly.
3. After Histamine and Carbachol treatment, the pepsinogen granules are formated continuously and reaccmulated as control after 3 to 4 hours.
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학술진흥재단(KCI)