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KMID : 0359319910310010099
Korean Journal of Veterinary Research
1991 Volume.31 No. 1 p.99 ~ p.108
Studies on the electrophoretic analysis of serum proteins in dogs infected with Babesia gibsoni




Abstract
To observe the changes of serum proteins according to the process of Babesia gibsoni(B gibsoni) infection, the babesia protozoa(10^8/㎏) were inoculated into the cephalic vein of healthy dogs. The serum proteins of experimentally infected dogs were separated by using cellulose acetate electrophoresis.
The results obtained were as follows;
1. Cellulose acetate electrophoresis was fractionated to total 6 of bands such as, albumin, α₁,α₂,β₁,β₂and γ-globulin.
2. The concentration of total protein was shown a decreasing tendency after B gibsoni infection. Albumin and A/G ratio were lowered through all periods of the infection, but they were not significant changes.
3. The level of α₁,-globulin was significantly(p<0.05) increased in early stage of the infection.
4. The levels of α₂ and total α-globulin were shown highly significant decreases (p<0.01) through all periods of the infection.
5. The levels of β₁, and total β-globulin had highly significant changes (p<0.01) that was increased in early stage of infection and decreased later.
6. The level of γ-globulin was seen to he constantly increased through all periods of infection. It was a highly significant change (p<0.01).
7. Plasma protein: fibrinogen (PP:F) ratio was shown a temporally significant increase (p<0.05) following the decrease in early infection.
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학술진흥재단(KCI)