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KMID : 0359319930330030419
Korean Journal of Veterinary Research
1993 Volume.33 No. 3 p.419 ~ p.427
Studies on the Clostridium perfringens type C infection of pig in Korea



Abstract
Thirteen strains of Clostridium perfringens were isolated from the pigs with hemorrhagic enteritis. The characteristics of the outbreaks, clinical signs and lesions were examined. The biochemical properties, type of toxin and susceptibility to antimicrobial agents of the isolates were investigated.
The results could be summarized as follows ;
1. Almost of the pigs affected with hemorrhagic enteritis, 17 cases examined from 1989 to 1992, were piglets less than 7 day old.
2. The average mortality rate of piglet less than 7 day old affected with hemorragic and necrotic enteritis was 48.5%.
3. The clinical signs of pigs with hemorrhagic entritis were depression, hemorrhagic diarrhea, anemia and dehydration. Necropsy of the infected pigs showed typical hemorrhage of upper intestine and necrosis of mucosal membrane.
4. The characteristic biochemical properties of the isolates were 2-band hemolysis, positive reaction of reverse CAMP test and formation of LV precipitate in egg yolk medium.
5. The toxin type of the 13 isolates, investigated by mouse inoculation test, was all type C strains of Clostridium perfringens.
6. In susceptibility test to antimicrobial agents, 13 isolates of Clostridium perfringens were highly sensitive to ampicillin, enrofloxacin(Baytril), cephalothin, penicillin and trimethoprim-sulfamethoxazole.
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학술진흥재단(KCI)