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KMID : 0359319960360040821
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Korean Journal of Veterinary Research
1996 Volume.36 No. 4 p.821 ~ p.828
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Neuromodulation on neurogenic contraction of electrical nerve stimulation on isolated renal artery of rabbit
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Abstract
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To elucidate the neuromodulation of neuropeptide Y and α, β-methylene ATP on the neurogenic contraction of electrical perivascular nerve stimulation and the contractile response of noradrenaline from polygraph in the isolated renal artery of rabbit.
1. The neurogenic contraction induced by perivascular nerve stimulation was the voltage-dependent manner(10-100V) in the isolated renal artery of rabbit.
2. Neuropeptide Y(0.1uM) and α, β-methylene ATP(1uM) increased the contractile responses of noradrenaline in the isolated renal artery of rabbit.
3. Neuropeptide Y(0.1uM) and α, β-methylene ATP(1uM) increased the neurogenic contraction of electrical perivascular nerve stimulation in the isolated renal artery of rabbit.
These results suggest that neuropeptide Y and α, β-methylene ATP neuromodulated on the neurogenic contraction of electrical perivascular nerve stimulation on the isolated renal artery of rabbit.
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