KMID : 0359320090490030231
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Korean Journal of Veterinary Research 2009 Volume.49 No. 3 p.231 ~ p.236
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Relationship between biofilm formation and the antimicrobial resistance in the Staphylococcus spp. isolated from animal and air
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Abstract
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Biofilm has been described as a barrier, which produced by microorganisms to survive and protect themselves against various environments, like antibiotic agents. Staphylococcus spp. is a common cause of nosocomial and environmental infection. Thirty-six and thirty-five Staphylococci were isolated from animals and air, respectively. Based on the biofilm forming ability of the bacterium reported in our previous report, relationship between biofilm formation and antibiotic-resistance was investigated in this study. Regarding antibiotics susceptibility, cefazolin was the most effective agent to the bacteria. Strong biofilm-forming Staphylococcus spp. isolates might have a higher antibiotic resistance than weak biofilm isolates regardless of the presence of antibiotic resistance genes (p < 0.05). This result suggested that the chemical complexity of the biofilm might increase the antibiotic resistance due to the decrease of antibiotic diffusion into cells through the extensive matrix.
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KEYWORD
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antibiotic susceptibility, biofilm, Staphylococcus spp.
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