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KMID : 0359320130530010001
Korean Journal of Veterinary Research
2013 Volume.53 No. 1 p.1 ~ p.5
Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran
Rassouli Maryam

Razmi Golam Reza
Movassaghi Ahmad Reza
Bassami Mohammad Reza
Sami Mehrdad
Abstract
The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs such as brain, liver, heart, lung, kidney, spleen) (4.6~14.4% with 95% CI) were positive in IHC with a very good logical agreement among different diagnostic techniques (κ = 0.73, 0.8) and with no significant difference among different fetal age groups (p > 0.05).
KEYWORD
histopathology, immunohistochemistry, Iran, ovine abortion, Toxoplasma gondii
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