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KMID : 0359320180580030143
Korean Journal of Veterinary Research
2018 Volume.58 No. 3 p.143 ~ p.146
Genetic variations in open reading frame 2 gene of porcine circovirus type 2 isolated in Korea during 2016-2017
Kim Ki-Ju

Choi Jong-Young
Lyoo Kwang-Soo
Hahn Tae-Wook
Abstract
The capsid protein of porcine circovirus type 2 (PCV2) encoded by open reading frame 2 (ORF2) is important for neutralizing activity against PCV2 infection. This study investigated the heterogeneity of the ORF2 gene of PCV2 isolated in Korea during 2016?2017. The results revealed that PCV2d is currently the predominant genotype. Moreover, comparison of ORF2 from 17 PCV2 isolates revealed 88.3?100% homology at the nucleotide (deduced amino acid 86.3?100%) level. Interestingly, 61.5% (8/13) of the PCV2d isolates had glycine at position 210. These data provide a useful information for PCV2 epidemiology in Korea.
KEYWORD
capsid proteins, genetic variation, phylogenetic analysis, porcine circovirus type 2
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학술진흥재단(KCI)