|
KMID : 03644199719970000109
|
|
East-West Medical Research Institute Journal
1997 Volume.1997 No. 0 p.109 ~ p.126
|
|
|
The effects of Sakunjatang and Samultang Aqua-acupuncture on Immune response
|
|
|
|
|
Abstract
|
|
|
In order to investigate the effects of Sakunjatang (M f-ig) and Samultang (VWM ) aqua-acupuncture on immune response, Sprague-Dawley male rats were used and randomly divided into four group. Normal group was normal control, Control group was injected i.v. with 2mg/kg MTX on 9th and 11th day after sensitization with SR.BC on 5th day, Sakunjatang aqua-acupunctured group(Sample A) was aqua-acupunctured daily for 18 days into the locus Q-1responding Bisu(B20) locus of the human body to Rat and MTX was administered 9t and 11th exlx~rimental day, Samultang aqua-acupunctured group(Sample B) was aqua-acupunctured-_.., fly for 18 days into the locus coresponding Bisu(B20) locus of the human body to Rat and MTX was administered 9th and 11th experimental day.
In the 9th day and the 11th day after aqua-acupuncture, MTX was injected to reduce immune function in the tail of rat. leukocyte count, lymphocyte ratio, lymphocyte count of splee, lymphocyte count of bonemarrow, contact hypersensitivity to DNFB, morphologic change of thymus cell, and electropherogram of serum protein.
The result were summarized as follows
1. Before MTX injection, leukocyte count had no significant difference in SakunjataN aqua-acupunctured group and Samultang aqua -acupunctured group compared to control group and after MTX injection, leukocyte count had no significant difference Sakunjatang aqua-acupunctured group and Samultang aqua-acupunctured group.
2. Before MTX injection, lymphocyte ratio was decreased significantly Sakunjatang aqua-acupunctured group and Samultang aqua -acupunctured group compared to control group.
3. After MTX injection, lymphocyte ratio was increased significantly Sakunjatang aqua-acupunctured group, Samultang aqua-acupunctured group had no significant difference compared to control group.
4. The lymphocyte count of spleen was increased significantly Sakunjatang aqua-acupunctured group and Samultang aqua -acupunctured group compared to control group.
5. The lymphocyte count of bonemarrow was increased significantly Sakunjatang aqua-acupunctured group, Samultang aqua-acupunctured group had no significant difference compared to control group.
6. Contact hypersensitivity was no significant difference in Sakunjatang aqua -acupunctured group and Samultang aqua-acupunctured group compared to control group.
7. In the morphologic change of thymus cell, control group comapred to normal group had a indistinct boundary between cortex and medulla, and lymphocyte cell density of thymus was low, Sakunjatang aqua-acupunctured group had a distinct boundary between cortex and medulla, and lymphocyte cell density of thymus was high.
8. In the SDS-PAGE electrophorogram of serum protein, Sakunjatang aqua-acupunctured group and Samultang aqua-acupunctured group had a wide band of nearby 50,000 and 25,000 Dalton which meant IgG generate more activity.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|