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KMID : 03772197919790000143
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Medical Journal of Chosun Univercity
1979 Volume.4 No. 1 p.143 ~ p.154
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The Effect of 3-Nutrients on the Duodenal Goblet Cells of the Rats
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노영복/No, Young-Bok
정주현/문정석/Chyung, Jue-Hyun/Moon, Jeong-Sock
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Abstract
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In our experiments we made use of male and female Swiss albiro rats weighing about 60gm each for the sake of investigating the duodenal goblet cells which mostly bring about secretory work.
The mice fed on three unbalanced diets consisting mostly of carbohydrate. protein and fat were the chief objects of study. on the 20th day after feeding, and after one or three day fasting, Specimens were taken from the upper, middle and lower portions of the duodenum the specimens were fixed in 10% formalir and made into paraffin secuions of 5μ and stainings were done with Hematoxylm-eosin. all or the goblet cells in each 20 crypts and villi, boths of which were cut in the axial directions were counted and averaged numbers were considered as total relative number of one animal.
The result were gained as follows
1 The relative number of the goblet cells in the duodenum of the mice fed on food averaged 22. 5. these cells were found more in the villi than in the crypts.
2. The relative number of the goblet cells in the mice fed on fat was larger than the normal value, and was the largest in the three groups fed on unbalanced diets.
3. The protein diet group was the smallest value among three groups.
4. The group´s goblet cells fasting 1-day increased a little in number relative to the normal.
5. The group´s goblet cells fasting 3-days increased the most in number of all groups.
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