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KMID : 03772198219820000141
Medical Journal of Chosun Univercity
1982 Volume.7 No. 1 p.141 ~ p.153
Studies on Serum Lipoprotein Patterns in Normal Korean Adults and Liver Diseases
Á¤Âù¿µ/Jung, Chan Yung
ÀÌÅ¿õ/¾çÈ¿±¸/¼ÛÇö°ï/Lee, Tae Woong/Yang, Hyo Koo/Song, Hyoun Kon
Abstract
Serum lipoprotein patterns were studied in 66 normal persons and 64 patients with acute hepatitis and in 57 patients with cirrhosis of liver at Asan Foundation Attached Hospital from 1980 to 1981.
Serum lipoprotein were seperated by electrophoresis with agarose gel and the following results were obtained.
1. In normal Korean, serum ¥á-lipoprotein showed decrements with aging, while serum ¥â-lipoprotein and pre-¥â-lipoprotein increased with aging, but the difference was not statistically significant. Significant alteration by sex in serum lipoprotein patternswere not observed.
2. Serum ¥á and pre ¥â-lipoprotein in patients with acute hepatitis gave lower value than in the normal persons, but the value of serum ¥â-lipoprotein were significantly elevated. Sex and age difference showed no statical significance in this disease.
3. The value of serum ¥á-lipoprotein fraction in patients with acute viral hepatitis B gave higher value than non-B acute viral hepatitis, but the difference was not statically significant.
4. Serum ¥á and pre-¥â-lipoprotein fraction in patients with icteric hepatitis showed decrement with increasing of serum total bilirubin level.
5. In the patients with cirrhosis of liver, the value of ¥á-lipoprotein was lower than normal subjects and patients with acute hepatitis, but (serum ¥â-lipoprotein fraction was higher than normal subjects and patients with acute hepatitis.
6. Serum ¥á-ilpoprotein fraction in patients with chronic hepatic encephalopathy was significantly lower then patients with cirrhosis of liver, but markedly higher value of serum ¥â-lipoprotein than cirrhosis of liver was observed.
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