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KMID : 0615219840090010029
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Journal of Kwangju Health
1984 Volume.9 No. 1 p.29 ~ p.40
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Interaction of dietary Mg(Ⅱ), Ca(Ⅱ) and polyunsaturated fatty acids on 3-Hydroxy-3-Methylglutaryl Co-A reductase activity
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남현근
김승호
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Abstract
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Interaction of dietary Magnesium, Calcium, and polyunsaturated fatty acids (vegetable oils) on 3-Hydroxy-3-Methylglutaryl Co-A reductase activity was studied for as period of 30 days using isocalories and isonitrogenous as a basal dist.
The subjed rabbits were divided into 18 feeding groups.
The results are summaried as follows:
1. The ratio of α₁-lipoprotein per lipalbumin is 0.34 for control group, 0.38, the highest, group fed 0. lM ㎎(Ⅱ) (10㎖) plus perilla oil and basal diet, the lowest, 0.25, group fed 0. lM ㎎(Ⅱ) (5㎖) pisu sesame oil and basal diet.
2. The ratis of α₂-lipoprotein per lipalbumin is 0.64 for control group, 0.95, as she highest for the group fed 0. lM Ca( Ⅱ ) (15㎖) plus sesame oil and basal diet, 0.25, as the lowest, for the groups fed 0.lM ㎎(Ⅱ) (5, 10㎖) plus Soybean oil and basal diet, 0.lM Ca(Ⅱ) (5㎖) plus perilla oil and basal diet.
3. The ratio of β-lipoprotein per lipalbumin is 0.71 for control group, the highest, 0.80 for the groups fed 0. lM ㎎(Ⅱ) (10㎖) plus sesame oil and basal diet, the louest, 0.37 for the group fed 0. lM ㎎(Ⅱ) (15㎖) plus Soybean oil and basal diet.
4. In serum triglyceride, control group was 129.5㎎%, the highest, 155.4㎎% for the group fed 0.lM Ca(Ⅱ) (5㎎) plus sesame oil and basal diet, the lowest, 85.7㎎% for the group fed 0.lM ㎎(Ⅱ) (10㎖) plus Soybean oil and basal diet.
5. In serum cholesterol, control group was 96.7㎎%, the hightest, 152.5㎎% for the group fed 0.lM Ca(Ⅱ) (10㎖) plus sesame oil and basal diet, the lowest, 80.5㎎% for the group fed 0.lM ㎎(Ⅱ) (15㎖) plus soydean oil and basal diet.
6. In case of H㎎-Co A reductase activity, control group was 0.95, the highest, 0.98 fer the group fed 0.lM Ca(Ⅱ) plus soybean oil and basal diet, the lowest, 0.82, for the group fed 0. lM ㎎(Ⅱ) (10㎖) plus seame oil and basal diet.
7. Interaction betueen Metal ions and polyunsaturated fatty acid(vegetable oil) are soybean oil>sesame oil>perilla oil for ㎎(Ⅱ), soybean oil>perilla oil>sesame oil for Ca(Ⅱ). Therefore, It is investigated that the interaction between metal ion and polyunsaturated fatty acid is the higher, the cholesterol level is the lower, and HMG-Co A reductase activity is increased.
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