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KMID : 0615219850100010025
Journal of Kwangju Health
1985 Volume.10 No. 1 p.25 ~ p.31
The Effect of thyroid Hormone on the Cholesterol and Phospholipid Concentration
남현근
Abstract
The effect of triiodotyronine-induced alteration of the cholesterol and phospholipids has been investigated. The results are follows:
1. There is no special influence to the body weight and liver weight changes.
2. In case of cholesterol, there is some increased serum cholesterol level in hyperthyroid state rabbit, cholesterol in mitochondria and microsome appeared lowering effect. (P<0.01)
3. In case of phospholipids, there is some increased serum phospholipids and phospholipipids in mitochondria, but there is lowering effect in microsomes. (P<0.01)
4. In case of fatty acids, linoeic acid is decreased but arachidonic acid is increased in mitochondria and microsomes. In the biological cell, the linoleic acid is converted to arachidonic acid.
It is, therefore, investigated that serum cholesterol level is increaesed by the cell membrane fluidity increasing for hyperthyroidism.
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