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KMID : 0615219880130010029
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Journal of Kwangju Health
1988 Volume.13 No. 1 p.29 ~ p.35
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Influence of Perilla Oil on the Activity of HMG-CoA Reductase and Fatty Acid Content in Liver Microsome of the Rabbit
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김동필/Kim DP
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Abstract
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The lowering concentration of cholesterol, fatty acid, phospholipid of liver microsome and the activity of HMG-CoA reductase of the liver microsome by feeding rabbits on perilla oil has been examined. The results are follows:
1. In case of the cholesterol and lipoprotein, the group of rabbits fed on perilla oil showed less than control group. Proportion of HDL was higher than LDL in rabbits fed on perilla oil. So it shows that perilla oil increases HDL.
2. Phospholipid of liver microsome in the group fed on perilla oil was richer than control group. Therefore it is assumed that perilla oil contributes to penetrate through cell-membrane of fetty acid.
3. Activity of HMG-CoA reductase to cholesterol was high in the group fed on perilla oil compared with control group.
4. It is assumed that α-linolenic acid perilla oil can be changed into C_(20:5) and C_(22:6) throughout the fatty acid content of liver microsomes.
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