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KMID : 0878620020060020081
Korean Journal of Pediatric Anesthesia
2002 Volume.6 No. 2 p.81 ~ p.85
Clinical Investigation of Severe Hypoxemia Immediately after Weaning from Cardiopulmonary Bypass during Surgery
Han Jong-In

Kim Dong-Yeon
Abstract
Background: Children, especially infants, have been shown to have compromised lung function after cardiac operation. However, little is known about the specific characteristics and etiology of hypoxemia immediatdy after cardiopulmonary bypass. So we analyzed 52 cases clinically to review the postbypass hypoxemia for congenital bean disease.

Methods: 52 children with congenital heart disease undergoing open
heart surgery with cardio-pulmonary bypass were analyzed retrospectively.

Results: Of the 52 cases, 1 year-old and under were 37 and over 1 year-old were 15 cases. The rate of male vs female was 30 : 22 of the operative diseases, ventricular septal defect (50%), atrial septal defect (17.3%), tetralogy of Fallot (9.6%) and other diseases (23.1%). Arterial oxygen partial pressure and alveolar-arterial oxygen difference were significantly different between over 1 year-old group and I year-old and under group immediately after, 30 minute and 60 minutes after weaning from bypass. Of the 7 cases had got severe hypoxemia after bypass, 6 cases were under 1 year-old and only 1 case was over 1 year-old.

Conclusions: We reported that under 1 year-old infant were at the risk of hypoxemia immediately after cardiopulmonary bypass for congenital heart disease surgery. This report can be used as a pilot study for the advanced randomized prospective study for the safety and benefits when operating on congenital heart disease infants.
KEYWORD
Complication, hypoxia, Heart, cardiopulmonary bypass, Surgery, cardiac, pediatric
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