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KMID : 08793200120010010057
Annuals of Clinical Study - Seoul National Hospital
2001 Volume.2001 No. 1 p.57 ~ p.64
Compliance of Nasal Continuous Positive Airway Pressure(nCPAP) Treatment in patients with Obstructive Sleep Apnea Syndrome
¿Àµ¿¿­/Oh DY
°­°æ¼÷/ÀÌ¿µÅÂ/Kang KS/Lee YT
Abstract
Objectives : Patients with the obstructive sleep apnea syndrome(OSAS) who have initiated nasal continuous positive airway pressure(nCPAP) treatment are strongly recommended to use nCPAP long-term basis in order to prevent recurrence of symptoms. We have reviewed our experience over a five-yeat period in OSAS patients referred to our sleep center for continuous positive airway nCPAP trials and evaluated long-term nCPAP compliance in patients using the device and factors influencing it.

Methods : We reviewed the records of 120 consecutive patients with OSAS referred to Division of Sleep Studies for nocturnal polysomnography with nCPAP pressure titration during the period of January 1995 through April 1999. And we performed a telephone interview with each of them on October 1999 and obtained data from 83 patients. Age, sex, education years, respiratory disturbance index(RDI), mean oxygen saturation, body mass index(BMI), prescribed nCPAP pressure, presence of subjective daytime sleepiness, presence of earlier uvulopalatopharyngoplasty(UPPP), and past history of hypertension were compared in the patients using nCPAP device more than 6 months and the patients using it less than 6 months.

Results : Out of 83 patients, 23 patients(27.7%) refused the recommended nCPAP treatment(these were more often low-educated). Of the remaining 60 patients, 34 patients(56.7%) had discontinued nCPAP treatment, primarily because of discomfort of use, while 26 patients(43.3%) were still using nCPAP device at the time of the telephone interview(the 24.6th¡¾14.5 months, mean¡¾SD). Only 15 patients(25%) were using nCPAP device everyday. Out of 34 patients who discontinued nCPAP use 25 patients(73.5%) did within the first 3 months, and 31(91.2%) within the first 1 year. There were no statistically significant differences between the patients using nCPAP device more than 6 months and the patients using it less than 6 months in age, sex, education years, baseline RDI, BMI, mean oxygen saturation, prescribed nCPAP pressure, presence of earlier UPPP, and past history of hypertension. Subjective daytime sleepiness was present before nCPAP application in 29 of the 35 patients using nCPAP device more than 6 months and in 14 of 25 patients using it less than 6 months(p<0.05).

Conclusions : In our study, the long-term compliance rate is relatively lower than those in the previous studies done in other countries. Increased long-term compliance with nCPAP treatment appears to be associated with the presence of subjective daytime sleepiness before nCPAP application. Long-term compliance with nCPAP may be mostly predicted from the usage pattern within the 3 months of use.
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