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KMID : 1021120110230020183
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Korean Journal of Occupational and Environmental Medicine
2011 Volume.23 No. 2 p.183 ~ p.191
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Association Between Blood Lead Concentration and Computerized Neurobehavioral Performance in Korean Elementary School Students
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Kim Yeon-Cheol
Jeon Man-Joong
Hong Yong-Tae
Lee Chul-Gab
Ha Mi-Na
Kwon Ho-Jang
Sakong Joon
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Abstract
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Objectives:This study was conducted to evaluate association between computerized neurobehavioral performance and blood lead concentration in Korean elementary school students.
Methods: The subjects were 1,077 elementary school students of Seoul, Busan, Daegu and Gwangju. Blood lead concentration was measured and computerized neurobehavioral performance tests were performed.
Results: Blood lead concentration of the subjects was in the range of 0.20 and 7.39 ㎍/㎗. The geometric mean of the subjects’ blood lead concentration was 1.41 ㎍/㎗. As blood lead concentration increased, reaction time to the symbol digit tended to increase significantly and linearly. As a result of LOWESS(locally weighted scatterplot smoothing), increasing reaction time to the symbol digit was observed.
Conclusions : As blood lead concentration under the CDC (center for disease control and prevention) reference value increased, reaction time to the symbol digit tended to increase. But, as the number of subjects over 3 ㎍/㎗ is small, it is difficult to make a definite conclusion. If confounding variables are controlled properly in a follow-up study, we can obtain a more definite conclusion.
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KEYWORD
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Computerized neurobehavioral performance, Blood lead concentration, Elementary school students
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