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KMID : 1021120120240030311
Korean Journal of Occupational and Environmental Medicine
2012 Volume.24 No. 3 p.311 ~ p.318
An Occupational Erythema Multifome Case of a Worker Exposed to Dichlone and 3,3¡¯-Dichlorobenzidine in a Dye Manufacturing Process
Yong Jae-Seung

Kim Jung-Won
Kim Eun-A
Abstract
Background: In Korea, the only case of occupational erythema multiforme was found to be due to Bolivian rosewood, but there has been no case due to occupational chemicals in the manufacturing industry. Here, we report a case of erythema multiforme caused by dichlone and 3,3¡¯-dichlorobenzidine(DCB) in a dye worker.

Case report: We report a 43-year-old male worker manifesting erythema multiforme-like skin lesions during the DCB synthesis, The patient¡¯s dermatitis was relieved when he avoided the process, and it became aggravated when he restarted his work. Patch and prick tests confirmed positive irritant reactions to two chemicals.

Conclusion: This case was diagnosed as erythema multiforme based on clinical manifestations. Symptoms worsened upon exposure to chemicals while avoiding exposure improved symptoms. Skin test results showed that dichlone and 3,3¡¯-dichlorobenzidine induced irritant reactions. We assume that erythema multiforme occurring in workers is an occupational skin disease likely caused by dichlone and 3,3¡¯-dichlorobenzidine.
KEYWORD
Erythema multiforme, Occupational, Contact dermatitis, 3, 3¡¯-Dichlorobenzidine, Dichlone
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