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KMID : 1039320140140020127
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Journal of Liver Cancer
2014 Volume.14 No. 2 p.127 ~ p.130
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A Case of Positive Tumor Marker Response after Intra-arterial Deferoxamine Infusion Therapy in a Hepatocellular Carcinoma Patient with Decompensated Liver Function
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Kim Hyun-Ju
Kang Won-Seok
Kim Mi-Na
Kim Beom-Kyung
Kim Seung-Up
Kim Do-Young
Ahn Sang-Hoon
Han Kwang-Hyub
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Abstract
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Treatment of hepatocellular carcinoma is often very challenging when the underlying liver function is decompensated. Recent experimental and clinical studies showed that some chelating agents, including deferoxamine, display anti-proliferative actions against tumor cells, thereby exhibiting anti-cancer effect in certain cancers, including hepatocellular carcinoma. Based on previous studies, we herein offer our experience of positive tumor marker response after intra-arterial deferoxamine infusion in a patient presenting with advanced hepatocellular carcinoma with decompensated hepatic function. Validation of the efficacy of intra-arterial deferoxamine therapy in the setting of advanced hepatocellular carcinoma with underlying decompensated hepatic function is warranted.
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KEYWORD
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Hepatocellular carcinoma, Decompensated liver cirrhosis, Deferoxamine
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