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KMID : 1039320170170010072
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Journal of Liver Cancer
2017 Volume.17 No. 1 p.72 ~ p.76
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A Case of Hepatocellular Carcinoma with Pulmonary Metastasis Who Showed Complete Response by Cytotoxic Chemotherapy after Sorafenib Failure
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Park Hwa-Sun
Jang Jae-Young
Baek Min-Young
Kim Yong-Kwon
Youn Hyun-Jin
Back Su-Young
Jeong Soung-Won
Lee Sae-Hwan
Kim Sang-Gyune
Cha Sang-Woo
Kim Young-Seok
Cho Young-Deok
Kim Hong-Soo
Kim Boo-Sung
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Abstract
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Hepatocellular carcinoma (HCC) is the 2nd most common cause of cancer related death in Korea and well-known malignancy with poor prognosis. Sorafenib is the first-line molecular targeted agent in patients with extra-hepatic spread of HCC. However, complete response is extremely rare in patients treated with sorafenib and the disease control rate is only 43%. We report a 53-year-old man with advanced HCC with pulmonary metastasis who showed complete response by cytotoxic chemotherapy with doxorubicin and cisplatin with relatively tolerable adverse effects after failure of treatment with sorafenib.
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KEYWORD
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Hepatocellular carcinoma, Pulmonary metastasis, Cytotoxic chemotherapy, Sorafenib
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