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KMID : 1039320190190020085
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Journal of Liver Cancer
2019 Volume.19 No. 2 p.85 ~ p.90
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Liver Transplantation in Mixed Hepatocellular Carcinoma and Cholangiocarcinoma
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Kim Jong-Man
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Abstract
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Mixed hepatocellular carcinoma and cholangiocarcinoma (HCC-CC) are rare tumors, and the risk factors associated with them are not well understood yet. Moreover, the diagnosis of mixed HCC-CC can be complicated due to the difficulty in distinguishing mixed HCC-CC from HCC and intrahepatic CCC on radiological images. Serum tumor markers are useful when the radiological images are inconclusive. It remains unclear whether the prognosis of mixed HCC-CC differs from that of HCC. However, several studies have reported that the tumor recurrence and patient survival rates of mixed HCC-CC were similar to those of HCC after liver transplantation (LT) and liver resection. In this paper, we report that LT in patients with mixed HCC-CC achieves outcomes which are similar to those seen in LT for HCC. Therefore, the diagnosis of mixed HCC-CC should not be considered as a contraindication for LT.
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KEYWORD
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Liver transplantation, Liver malignancy, Outcomes
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