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KMID : 1039620120020010024
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Korean Journal of Family Practice
2012 Volume.2 No. 1 p.24 ~ p.29
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Pharmacotherapy of Depression in Primary Care
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Kim Young-Sik
Cho Jung-Jin
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Abstract
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Depression is a highly prevalent mental health disease that, fortunately, can be treated in many cases with ntidepressants.
Proper depression management plans help depressive patients adhere to medication treatment to reduce suicidal ideation and behavior. However, one third of patient may not respond suffi ciently to the fi rst-line antidepressants. The primary care physician treating depression should understand the characteristics of various antidepressants and also the optimal treatment strategy. We discuss antidepressant treatment options with the person with depression, covering the choice of antidepressant, including any anticipated adverse events, for example side effects and discontinuation symptoms. According to current guidelines for depression in primary care, the first-line drug should normally be the ’newer’ ntidepressants, including selective serotonine reuptake inhibitors, because they are equally effective as other
antidepressants and have a favourable risk?benefit ratio. Treatment courses of depressive disorder can be divided into
remission in acute phase, continuation phase, and maintenance period, so that medication of antidepressants should be
optimized for each phase.
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KEYWORD
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Depression, Primary Care, Antidepressive Agents
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